Exercise: You may need less than you think

An intersting read #dailyexerciseguidelines

Raspberry Streusel Bars April 22, 2021
Raspberry Streusel Bars: Scrumptious berry bars with a melt in your mouth oatmeal crumb topping and fresh or frozen berries! With a sweet oatmeal crust, a layer of fresh berries and jam plus a crumble topping, how could you resist these divine Raspberry Bars? (more…) The post Raspberry Streusel Bars appeared first on That Skinny […]
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How I Moved from Depression to a Deep and Meaningful Life April 22, 2021
“Only to the extent that we expose ourselves over and over to annihilation can that which is indestructible be found in us.” ~Pema Chödrön Standing at the bathroom sink, I brought my gaze up to the mirror. I couldn’t avoid eye contact with the one person I had no desire to talk to. I had […]
Tiny Buddha
Pineapple Pie April 22, 2021
This delicious and sweet homemade pineapple pie is absolutely one of the easiest desserts you will ever make! With just 5 ingredients, it’s one of my favorite easy summer recipes. One taste of the traditional pineapple pie filling and buttery flaky crust makes you feel like you’re lounging on a tropical Hawaiian beach. Every time […]
Chocolate Covered Katie – The Healthy Dessert Blog
425 A superfacial ulcer on the scrotum April 22, 2021
A 54-year-old man presented to the dermatology clinic with an itchy red papule on the right scrotum for 2 years, which gradually expanded to a yellow central ulcerated plaque and the crust was not easy to be removed. Topical mupirocin and corticosteroids were not effective. Fluorescent microscopy for fungus was negative, as well as antibodies […]
Journal of Investigative Dermatology
367 Entropion repair outcomes in ocular cicatricial pemphigoid versus other cicatricial etiologies: A retrospective study April 22, 2021
Mucous membrane pemphigoid with ocular involvement or ocular cicatricial pemphigoid (OCP) can lead to severe eyelid disease, including entropion. Surgical repair outcomes of OCP-related entropion compared to other cicatricial entropion has yet to be elucidated. This study aims to understand the association between entropion recurrence and diagnosis of OCP. Entropion repair of OCP patients were […]
Journal of Investigative Dermatology
431 Correlation of the peripheral blood CD4/CD8 ratio with the disease stage and overall survival in mycosis fungoides April 22, 2021
Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma. The cutaneous manifestation of MF ranges from a patch stage to a more severe plaque or tumor stage. A hallmark of MF is an increased CD4+ T cell population, which results in a high CD4/CD8 ratio. Previous studies have shown the CD4/CD8 ratio […]
Journal of Investigative Dermatology
399 Interim analysis of a real-world retrospective multicenter study: Evaluation of effectiveness of secukinumab in adult patients with moderate-to-severe plaque psoriasis in China April 22, 2021
There is a growing body of real-world evidence globally indicating secukinumab is effective in treating patients with moderate-to-severe plaque psoriasis. However, there is a paucity of real-world evidence on treatment effectiveness in China. We present results of an interim analysis of a study on a cohort of adult patients with moderate-to-severe plaque psoriasis, who initiated […]
Journal of Investigative Dermatology
143 Skin barrier dysfunction initiates psoriasis inflammation via activating FPR1-ER stress-NLRC4 axis in keratinocytes April 22, 2021
Decreased skin barrier function may aggravate or even initiate psoriasis, and aiding barrier reestablishment using emollients helps improve the psoriatic symptoms, but the mechanisms for such changes have remained unclear. Here we show that epidermal barrier defect caused by tape stripping or topical use of acetone exacerbates the psoriasis-like inflammation, such as increasing the expressions […]
Journal of Investigative Dermatology
463 Automated atopic dermatitis severity assessment based on convolutional neural networks April 22, 2021
Convolutional neural networks (CNNs) is artificial intelligence (AI) neural network that can provide a binary or multiclass classification for the diagnosis of various skin disorders. However, there has been a challenge to predict the severity of skin disorders with CNNs. Here we investigated the optimal preprocessing conditions and performance of trained CNN models to grade […]
Journal of Investigative Dermatology
271 “Moisturize and get off any steroid cream”: An analysis of social media posts regarding TCS use in AD April 22, 2021
Analyses of online interactions among atopic dermatitis (AD) patients are limited. This study aims to analyze the content and engagement of online posts on topical corticosteroid (TCS) use in AD. Of 2047 posts extracted from 5 social media groups, 949 referenced TCS safety, defined as a higher-order theme (HOT). Within the HOT of TCS safety, […]
Journal of Investigative Dermatology